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THE EFFECTS OF TWO ANTIDEPRESSANT AGENTS ON PERFORMANCE ON THE STROOP COLOUR‐WORD TEST IN NORMAL MALE VOLUNTEER SUBJECTS
Author(s) -
HARVEY P.G.,
CLAYTON A.B.,
BETTS T.A.
Publication year - 1978
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1978.tb01712.x
Subject(s) - imipramine , volunteer , placebo , stroop effect , antidepressant , medicine , pharmacology , psychology , psychiatry , alternative medicine , pathology , cognition , agronomy , biology , hippocampus
1 Healthy male volunteers were given either imipramine (25 mgs three times a day), viloxazine hydrochloride (Vivalan) (50 mgs three times a day), placebo or no tablets on a double‐blind basis. 2 Subjects took the tablets for 7 days, and were tested before treatment and then after 1, 7 and 21 doses. 3 The Stroop Colour‐Word test was used to assess performance. 4 While no significant drug effects were found it is suggested that some of the trends shown are indicative of a slight worsening of performance with imipramine and a slight improvement with viloxazine hydrochloride after seven doses.