Premium
The acute effects of the administration of rimiterol aerosol in asthmatic children.
Author(s) -
Blackhall MI,
Macartney B,
O'Donnell SR
Publication year - 1978
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1978.tb01682.x
Subject(s) - bronchodilation , orciprenaline , bronchodilator , medicine , crossover study , microgram , anesthesia , bronchodilator agents , pulse rate , asthma , chemistry , blood pressure , biochemistry , alternative medicine , pathology , in vitro , placebo
1 Ten asthmatic children received on two separate occasions rimiterol (500 microgram) and orciprenaline (1.5 mg) as aerosols in a double‐ blind, crossover design trial. Respiratory parameters (FEV1, FVC and PEFR) and pulse rate were recorded for 60 min after each administration. 2 Rimiterol produced effective bronchodilation in children with negligible cardiac stimulation. It differed from orciprenaline in that the peak bronchodilator effect was not maintained during the 60 min observation period. 3 Rimiterol is a selective, short‐ acting, sympathomimetic bronchodilator in children.