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Catecholamine sensitivity in hyperthyroidism and hypothyroidism.
Author(s) -
McDevitt DG,
Riddell JG,
Hadden DR,
Montgomery DA
Publication year - 1978
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1978.tb00855.x
Subject(s) - euthyroid , isoprenaline , medicine , endocrinology , catecholamine , thyroid dysfunction , thyroid , stimulation
1. Catecholamine sensitivity in hyper‐ and hypothyroidism has been studied using a standardised isoprenaline sensitivity test. 2. Seven patients with hyperthyroidism and seven with hypothyroidism were tested both when showing evidence of thyroid dysfunction and again when euthyroid. 3. No significant differences were seen in heart rate responses to isoprenaline when patients became euthyroid compared to their response when either hyperthyroid or hypothyroid. 4. These results indicate that sensitivity to catecholamines is not altered in thyroid dysfunction and, in particular, that hypersensitivity does not occur in spontaneous hyperthyroidism.