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Experience with the use of a corticosteroid aerosol.
Author(s) -
Chatterjee SS
Publication year - 1977
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1977.tb04516.x
Subject(s) - medicine , corticosteroid , asthma , microgram , incidence (geometry) , aerosol , chemistry , organic chemistry , biochemistry , physics , optics , in vitro
1. In 48 patients with chronic asthma who had been receiving treatment with beclomethasone dipropionate aerosol (BDA) at a daily dose of 400 microgram for several years, observations were made on the effect of increasing the dose to 800 microgram daily for 6 months. 2. There was subjective improvement in 37 of the 48 patients, but the only objective evidence of improvement was a slight reduction in airways resistance. 3. The higher dose of BDA did not produce impairment of pituitary‐ adrenal function or an increase in the incidence of oropharyngeal candidiasis.