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Fluorimetric assay of cephradine, cephalexin and cephaloglycin.
Author(s) -
Barbhaiya RH,
Turner P
Publication year - 1977
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1977.tb00757.x
Subject(s) - cephradine , fluorescence , chemistry , formaldehyde , antibiotics , chromatography , biochemistry , cephalosporin , physics , quantum mechanics
1 A simple, rapid and reproducible fluorimetric assay for cephradine, cephalexin and cephaloglycin is described. 2 The method involves addition of formaldehyde which catalyses the formation of fluorescent derivatives. 3 The structural similarities between the side chains of these antibiotics and their identical excitation and emission spectra suggest that they may be forming similar fluorescent derivatives.