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ABSORPTION OF DRUGS BY THE LUNG
Author(s) -
SHENFIELD GILLIAN M.,
EVANS MARION E.,
PATERSON J.W.
Publication year - 1976
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1976.tb04879.x
Subject(s) - salbutamol , sodium cromoglycate , pharmacology , medicine , absorption (acoustics) , lung , sodium , asthma , anesthesia , chemistry , materials science , organic chemistry , composite material
1 Ten patients undergoing diagnostic bronchoscopy had radioisotopically labelled drugs put directly into their bronchi; two received sodium cromoglycate, two salbutamol, three salmefamol and three rimiterol. 2 All four drugs were rapidly absorbed but higher peak plasma levels per unit dose were seen with sodium cromoglycate and salbutamol than with the other two drugs. 3 It is suggested that the lung metabolizes salmefamol and rimiterol but does not metabolize salbutamol or sodium cromoglycate.