Premium
The acute and chronic bronchodilator effects of ephedrine in asthmatic patients.
Author(s) -
May CS,
Pickup ME,
Paterson JW
Publication year - 1975
Publication title -
british journal of clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.216
H-Index - 146
eISSN - 1365-2125
pISSN - 0306-5251
DOI - 10.1111/j.1365-2125.1975.tb00572.x
Subject(s) - ephedrine , bronchodilator , theophylline , medicine , bronchodilatation , anesthesia , bronchodilator agents , asthma , pharmacology
In eight asthmatic patients, there was no change in the bronchodilator response to a single dose of ephedrine (22 mg) given alone or in a compound tablet, after treatment with ephedrine (11 mg three times a day) or one tablet three times a day for 2 weeks. 2 There was no deterioration in lung function during the 2 week treatment period with either ephedrine or the compound tablet. 3 An inter‐patient variation was noted in the plasma ephedrine concentraition required for bronchodilatation. 4 The half‐life of theophylline did not change after chronic treatment with the tablets, one three times a day for 2 weeks.