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Studies on an experimental model for pancreas disease
Author(s) -
MURPHY T. M.,
DRINAN E. M.,
GAN F.
Publication year - 1994
Publication title -
aquaculture research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.646
H-Index - 89
eISSN - 1365-2109
pISSN - 1355-557X
DOI - 10.1111/j.1365-2109.1994.tb00683.x
Subject(s) - biology , pancreas , infectivity , inoculation , salmo , pathological , fish <actinopterygii> , physiology , medicine , microbiology and biotechnology , virology , endocrinology , immunology , fishery , virus
. Pancreas disease (PD) was induced by inoculating freshwater parr, Salmo salar L., with a homogenate of pooled tissues collected from four fish in the acute phase of disease. Pathological changes were observed in the liver and pancreas on day 4 post inoculation (PI) and in the heart on day 8 PI. Regeneration of necrotic acinar tissue was evident by day 8 PI. The infectious nature of PD was manifested by fish cohabiting with experimentally infected fish succumbing to PD after 13 days. The PD agent/agents retained its infectivity after filtration through a 0‐2‐μm filter.