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Non‐synonymous SNP s in MC 1 R gene are associated with the extended black variant in domestic ducks ( A nas platyrhynchos )
Author(s) -
Yu Wenhua,
Wang Cui,
Xin Qingwu,
Li Shijun,
Feng Yanping,
Peng Xiuli,
Gong Yanzhang
Publication year - 2013
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2012.02377.x
Subject(s) - biology , gene , snp , genetics , single nucleotide polymorphism , genotype
Summary In this study, we performed a sequence characterization of the duck melanocortin 1 receptor (alpha‐melanocyte stimulating hormone receptor) ( MC1R ) gene to analyze the relationship between MC1R polymorphism and the extended black variant in domestic ducks based on the extended black ( E ) and non‐extended black ( e + ) allele hypothesis of the duck MC1R gene. Both c.52G>A and c.376G>A substitutions are highly associated with the duck extended black variant ( P < 0.01), but the novel c.52G>A substitution is more of a fit for the allele hypothesis of the duck MC 1R gene.