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A linkage map of Sheep Chromosome X (OARX) aligned to Human Chromosome X (HSAX)
Author(s) -
French M. C.,
Dodds K. G.,
Davis G. H.,
Galloway S. M.,
Edwards S. J.
Publication year - 2011
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2010.02139.x
Subject(s) - biology , genetics , linkage (software) , breakpoint , genetic linkage , chromosome , genetic linkage map , chromosomal inversion , gene map , complete linkage , gene mapping , gene , karyotype , genotype , single nucleotide polymorphism
Summary We have constructed a genetic linkage map of the sheep X chromosome (OARX) containing 22 new gene loci from across the human X chromosome (HSAX). The female OARX linkage map has a total length of 152.6 cM with average gene spacing of 5.5 cM. Comparison with HSAX confirms one previously reported major breakpoint and inversion, and other minor rearrangements between OARX and HSAX. Comparison of the linkage map with sheep sequence data OAR 1.0 reveals a different arrangement of markers on the q arm, which may more accurately reflect the genuine arrangement of this region.