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The effects of the polymorphism in exon 3 of the FAS gene on the death of chicken embryos during the incubation period
Author(s) -
Wu J. J.,
Li W. M.,
Zhao R. X.,
Fang J.,
Wang C.,
Peng X. L.,
Li X.,
Xiong J. J.,
Yang L. G.,
Zhang S. J.
Publication year - 2008
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2008.01760.x
Subject(s) - biology , embryo , genotype , hatching , exon , genetics , snp , andrology , polymorphism (computer science) , gene , single nucleotide polymorphism , zoology , medicine
Summary To investigate the effect of a factor‐associated suicide ( FAS ) gene polymorphism on the death of chicken embryos, we genotyped 190 dead embryos and 69 normally developing embryos from 7200 hatching Short‐Leg Yellow Chicken eggs, as well as 119 dead embryos and 69 normally developing embryos from 4650 hatching Yellow B Chicken eggs. The results showed that there were significant ( P < 0.05) genotypic differences between dead and normally developing embryos for this FAS gene polymorphism, a SNP in exon 3 (NC_006093.2:g.6514A>C, rs15793179). Logistic regression revealed that Short‐Leg Yellow Chicken embryos with genotype g.6514CC had a significantly ( P < 0.01) higher risk of death than those with genotype g.6514AC. This polymorphism has the potential to be an effective tool when used in conjunction with traditional selection methods.