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Characterization of single nucleotide polymorphisms in sheep and their variation as evidence of selection
Author(s) -
Pariset L.,
Cappuccio I.,
Joost S.,
D'Andrea M.,
Marletta D.,
Ajmone Marsan P.,
Valentini A.
Publication year - 2006
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2006.01441.x
Subject(s) - biology , single nucleotide polymorphism , selection (genetic algorithm) , genetics , variation (astronomy) , genetic variation , evolutionary biology , genotype , gene , artificial intelligence , computer science , physics , astrophysics
Summary The discovery of SNPs was performed using animals from eight European sheep breeds. Eleven SNPs were further characterized using about 1700 sheep belonging to 57 breeds. A method for the identification of loci that were likely subject to selection was applied; three of the 11 SNPs lying outside the 95% confidence region of the conditional joint distribution of F ST and mean heterozygosity were identified as outliers.