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Physical mapping of eight pig genes whose expression level is acutely affected by Salmonella challenge
Author(s) -
Kim J. W.,
Zhao S.H.,
Uthe J. J.,
Bearson S. M. D.,
Tuggle C. K.
Publication year - 2005
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.2005.01309.x
Subject(s) - library science , ames test , disease control , salmonella , biology , gerontology , medicine , genetics , microbiology and biotechnology , computer science , bacteria
Source/description: The objective of this research was to map genes identified as having altered gene expression patterns within the mesenteric lymph nodes of swine during infection with Salmonella enterica serotype Choleraesuis (J. J. Uthe, T. J. Stabel, S. H. Zhao, C. K. Tuggle, S. M. D. Bearson, submitted). Seven genes increased and two decreased their expression levels within 24 or 48 h post-infection, and were identified using suppression subtractive hybridization (SSH). As several heat-shock protein genes were identified by SSH, an additional heat-shock gene family member (HSPA1A) was also tested and found to respond to infection as well (J. J. Uthe, T. J. Stabel, S. H. Zhao, C. K. Tuggle, S. M. D. Bearson, submitted).