Syntenic assignment of dopamine tautomerase (DCT) to bovine chromosome 12

Summary Heterologous primers were used to amplify an exon and intron‐containing segment of the bovine homologue of the human dopachrome tautomerase gene. After confirmation of homo‐logy by sequence analysis (exon sequence similarity greater than 90%), bovine‐specific primers were developed for synteny mapping purposes. The dopachrome tautomerase gene was assigned to bovine chromosome 12 (BTA12) with 97% concordance to the coagulation factor 10 locus. Together with previous synteny mapping of bovine chromosome 12 genes, fms‐related tyrosine kinase, esterase D and 5‐hydroxytryptamine receptor 2, this assignment further indicates conservation between human chromosome 13q and bovine chromosome 12.