Premium
Molecular characterization of the porcine MHC class I region
Author(s) -
Gaycken U.,
Shabahang M.,
Meyer J. N.,
Glodek P.
Publication year - 1994
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1994.tb00373.x
Subject(s) - cosmid , biology , restriction enzyme , genetics , restriction map , complementary dna , microbiology and biotechnology , mhc class i , gene , dna , major histocompatibility complex , base sequence
Summary A porcine cosmid library was screened with a human MHC class I cDNA. Four positive clones were isolated and mapped with different restriction endonucleases. Altogether nine SLA class I genes were identified and their positions located within restriction maps. Sizes of class I homologous DNA sequences varied between 3600 and 5800bp. The distances between these regions ranged from 11900 to 22200bp.