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High lysozyme activity in a Norwegian bovine family co‐segregates with a restriction fragment length polymorphism
Author(s) -
Olsaker I.,
Mejdell C. M.,
Sarensen A.,
Lie Ø
Publication year - 1993
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1993.tb00355.x
Subject(s) - lysozyme , restriction fragment length polymorphism , biology , genetics , locus (genetics) , restriction enzyme , norwegian , allele , terminal restriction fragment length polymorphism , polymorphism (computer science) , mendelian inheritance , microbiology and biotechnology , gene , genotype , linguistics , philosophy
Summary Analysis of restriction fragment length polymorphism (RFLP) of the lysozyme gene cluster was performed in a Norwegian bovine family segregating a single dominant Mendelian factor for high lysozyme activity in serum. An RFLP site with allelic bands of 16kb and 5–9 kb turned out to be linked to the locus for the high lysozyme activity factor with a lod score of 6–8 at a recombination fraction of 3.4%. This implies that we have revealed a genetic marker for the high lysozyme activity trait.