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Localization of the porcine growth hormone gene to chromosome 12pl.2 p1–5
Author(s) -
Yerle M.,
LahbibMansais Y.,
Gellin J.,
Thomsen P. D.
Publication year - 1993
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1993.tb00254.x
Subject(s) - biology , karyotype , chromosome , in situ hybridization , microbiology and biotechnology , growth hormone , genetics , gene , high resolution , hormone , gene expression , biochemistry , remote sensing , geology
Summary The gene encoding the porcine growth hormone (GH) has been localized to the q‐arm of chromosome 12 using high‐resolution R‐banded chromosomes for in situ hybridization. We report here the localization of GH on the p‐arm of this chromosome when using in situ hybridization on high‐resolution G‐banded chromosomes. Sequential Q‐ and R‐banding show that this discrepancy is caused by a reversed orientation of chromosome 12 in the R‐banded high‐resolution karyotype published by Rønne et al. (1987) and the G‐banded standard karyotype.