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Absence of evidence for linkage between Booroola gene and genetic markers at 11 sheep blood polymorphic loci
Author(s) -
NGUYEN T. C.,
ELSEN J. M.,
CULLEN P. R.
Publication year - 1992
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1992.tb00172.x
Subject(s) - biology , locus (genetics) , genetics , sire , allele , genetic linkage , genetic marker , offspring , gene , gene mapping , chromosome , pregnancy , zoology
Summary. Genetic linkage between the Booroola locus ( Fec ) and 11 sheep blood polymorphic loci (i.e. Tf, Hb, CA, OLA, and A, B, C, D, M, R, F41 red cell blood groups) was investigated in six large sire families (163 informative female offspring). The six sires tested were heterozygous for the Booroola allele ( Fec B ) and for several genetic markers. No evidence in favour of linkage was found. Moreover, depending on the marker locus considered, linkage closer than or as close as the recombination frequency of 10–30% was excluded.