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Mapping of bovine prolactin and rhodopsin genes in hybrid somatic cells
Author(s) -
HALLERMAN E. M.,
THEILMANN J. L.,
BECKMANN J. S.,
SOLLER M.,
WOMACK J. E.
Publication year - 1988
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1988.tb00798.x
Subject(s) - biology , somatic cell , rhodopsin , gene , genetics , somatic fusion , prolactin , microbiology and biotechnology , endocrinology , biochemistry , hormone , retinal
Summary. The genes encoding bovine prolactin and rhodopsin were assigned to syntenic groups on the basis of hybridization of DNA from a panel of bovine‐hamster hybrid somatic cell lines with cloned prolactin and rhodopsin gene probes. Prolactin was found to be syntenic with previously mapped glyoxalase, BoLA and 21‐hydroxylase genes, establishing a syntenic conservation with human chromosome 6. The presence of bovine rhodopsin sequences among the various hybrid cell lines was not concordant with any gene previously assigned to one of the 23 defined autosomal syntenic groups. Thus, rhodopsin marks a new bovine syntenic group, U24, leaving only five cattle autosomes unmarked by at least one biochemical or molecular marker.