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Class I major histocompatibility complex antigens and C4 concentrations in sheep plasma
Author(s) -
GROTH D. M.,
WETHERALL J. D.,
OUTERRIDGE P.,
STEAR M. J.
Publication year - 1987
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1987.tb00758.x
Subject(s) - biology , major histocompatibility complex , complement (music) , gene , antigen , histocompatibility , immunogenetics , immunology , genetics , human leukocyte antigen , phenotype , complementation
Summary. Data are presented demonstrating that high concentrations of complement protein C4 in sheep plasma are associated with a particular class I OLA specificity. By way of contrast, a similar association could not be demonstrated between C3 plasma concentrations and OLA specificities. These data support the hypothesis that gene(s) determining C4 plasma concentrations are linked to the ovine MHC.