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Genetic variation of the bovine thyroglobulin gene studied at the DNA level
Author(s) -
GEORGES M.,
LEQUARRÉ A. S.,
HANSET R.,
VASSART G.
Publication year - 1987
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/j.1365-2052.1987.tb00742.x
Subject(s) - biology , thyroglobulin , genetics , gene , dna , genetic variation , microbiology and biotechnology , antibody
Summary. The bovine thyroglobulin gene has been analysed for variation using restriction endonucleases. Six independent restriction fragment length polymorphisms have been identified. One of these results most probably from a 2.5‐kb deletion, the others being compatible with point mutations. We determined that an individual taken at random within the Belgian White and Blue breed is, on average, heterozygous for one out of 1700 nucleotides within the thyroglobulin gene.