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Restriction site polymorphisms in the pig β‐globin gene cluster
Author(s) -
Rando A.,
Masina P.
Publication year - 1985
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1985.tb01449.x
Subject(s) - biology , genetics , gene cluster , gene , globin , microbiology and biotechnology
Summary A restriction fragment length polymorphism was detected in pig DNA digested with Hind III restriction endo nuclease and probed with rabbit β 1 ‐globin gene. Eight different phenotypes were observed and for six of them family data demonstrated that they are determined by three alleles. As this polymorphism is not found with four other restriction endo nucleases (Bam HI, Eco RI, Kpn I, and Pst I), single point mutations are proposed to explain the observed differences.
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