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Genetic variation at a pig serum protein locus, Po‐2 and its assignment to the Phi, Hal, S, H, Pgd linkage group
Author(s) -
Juneja R. K.,
Gahne B.,
EdforsLilja I.,
Andresen E.
Publication year - 1983
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1983.tb01057.x
Subject(s) - locus (genetics) , genetics , biology , linkage (software) , genetic linkage , gene
Summary Two‐dimensional agarose gel (pH 5.4)‐polyacrylamide gel (pH 9.0) electropho‐resis of pig serum samples revealed a new serum protein (postalbumin‐2, PO‐2) polymorphism. Family data supported the hypothesis that the three PO‐2 phenotypes observed were controlled by two codominant, autosomal alleles ( Po‐2 F and Po‐2 S ) at a single locus. The frequency of Po‐2 F in Swedish Landrace and in Swedish Yorkshire breeds was estimated at 0.74 and 0.65, respectively. Evidence was presented for close genetic linkage between Po‐2 and the red cell phospho‐hexose isomerase locus ( Phi ). A recombination frequency of 3.2 % was obtained from double backcross material. Data obtained in a Danish Landrace material showing linkage between the Po‐2 locus and the H blood group locus, the Pgd locus and Hal (locus for halothane sensitivity) are also given. A total of seven re‐combinants were observed. They show that Po‐2 is a new locus in a previously established linkage group. The likely sequence of the loci is: Phi, Hal, S, H, Po‐2, Pgd .