Premium
Linkage studies between the halothane (Hal), phosphohexose isomerase (Phi) and the S(A ‐O) and H red blood cell loci of Pietrain/ Hampshire and Landrace pigs
Author(s) -
Imlah P.
Publication year - 1982
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1982.tb01568.x
Subject(s) - glucose 6 phosphate isomerase , biology , red cell , red blood cell , linkage (software) , genetics , microbiology and biotechnology , medicine , biochemistry , gene , enzyme
Summary Frequency of blood group factors at the A‐O and H loci were markedly altered within halothane positive (HP) and halothane negative (HN) composite synthetic Pietrain/Hampshire lines (PTH) over four generations of selection. Linkage studies on the litters from 45 double backcross and 20 mixed and intercross matings, involving the S(A‐O), H, Phi and Hal loci, were made in the PTH line and halothane positive and negative selected British Landrace lines. Crossing‐over frequencies of 0.05 ± 0.04, 0.05 ± 0.03 and 0.1 ± 0.03 were established between Phi and Hal, H and Hal , and Phi and H respectively. An unequal crossing‐over frequency between Phi and H was found when the alleles Ha and Hcd were compared. The difference in recombination frequency between the Ha and Hcd alleles amounted to 0.04 to 0.06. No cross‐overs were observed between the S(A ‐O ) and Phi, H or Hal loci in 15 families studied. The position of the S locus in relation to the other loci could not be established, but statistical evidence of association favours a haplotype sequence of Phi‐Hal‐S‐H .