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Genetic markers in Herd wick sheep: no correlation with succeptibility or resistance to experimental scrapie
Author(s) -
Collis Susan C.,
Millson G. C.,
Kimberlin R. H.
Publication year - 1977
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1977.tb01630.x
Subject(s) - scrapie , biology , genetics , isozyme , phenotype , albumin , genetic marker , herd , esterase , gene , enzyme , disease , prion protein , biochemistry , pathology , medicine , zoology
Summary Genetic markers were studied in Herdwick sheep, bred at Compton, with special reference to genetically selected lines which differ in susceptibility or resistance to experimentally produced scrapie. There were no correlations between susceptibility to the disease and albumin, pre‐albumin, esterase and haemoglobin phenotypes, and between reduced glutathione levels and α‐mannosidase isoenzymes, the latter possibly representing a previously undescribed genetic marker in sheep.