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Lymphocytotoxic antibodies against cattle J antigen
Author(s) -
Hruban V.,
Simon M.
Publication year - 1973
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1973.tb01296.x
Subject(s) - antibody , antigen , cytotoxic t cell , biology , immunology , microbiology and biotechnology , genetics , in vitro
The J substance is unique compared to all other known red cell antigenic characters of cattle blood because it is detected by naturally occurring antibodies and occurs dissolved in body fluids. Also it could be demonstrated by absorption techniques on the lymphocytes and platelets of the J‐positive animals (Eyquem et al., 1956). The presence of the J antigen on these tissues raises the question whether cytotoxic antibodies exist against it. This question has been studied and the first results are presented.