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Two erythrocytic lactate dehydrogenase variants in the house mouse, Mus musculus
Author(s) -
Martin J. E.,
Petras M. L.
Publication year - 1971
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1971.tb01225.x
Subject(s) - biology , locus (genetics) , house mouse , house mice , isozyme , laboratory mouse , lactate dehydrogenase , genetics , microbiology and biotechnology , enzyme , gene , biochemistry , zoology
Summary Two erythrocytic LDH variants have been found in the house mouse, Mus musculus. One, involving the presence and absence of the next to the slowest electrophoretically separable isozyme, is controlled by a regulatory locus which may be similar to Ldr‐1 (Shows and Ruddle, 1968). The second appears to be indirectly controlled by the Hbb locus and may be attributed to the accumulation of a storage product in the lysates. Ldr‐1 is polymorphic in natural populations of the house mouse.