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Iso‐antibodies to red cell antigens in pigs' sera. 1. Iso‐immunisation of pregnancy in sows
Author(s) -
Linklater K. A.
Publication year - 1971
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1971.tb01222.x
Subject(s) - antibody , antigen , biology , andrology , red cell , pregnancy , immunology , rh blood group system , medicine , genetics
Summary It has been demonstrated that iso‐immunisation of sows by foetal red cell antigens can occur. Four sows were shown to produce iso‐antibodies to the blood group factors Ea and Kb, after giving birth to Ea‐positive and Kb‐positive piglets, respectively. They did not produce the antibodies after giving birth to only Ea‐negative and Kb‐negative piglets, respectively. Two Ea‐negative gilts and a further Ea‐negative sow, all of which had no evidence of red cell iso‐antibodies in their sera were mated to an Ea‐positive boar. Anti‐Ea was detected in the sera of two of them for the first time after the subsequent parturition; the third remained negative. Complete and reliable life histories of all these animals were available. There were no previous injections of pig red cells in any form.