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Glucose‐6‐?hosphate dehydrogenase deficiency, haptoglobin and hemoglobin variants in dogs
Author(s) -
Naik S. N.,
Anderson D. E.,
Jardine J. H.,
Clifford D. H.
Publication year - 1971
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1971.tb01204.x
Subject(s) - haptoglobin , hemoglobin , biology , medicine , endocrinology , biochemistry
Summary Blood samples from 31 male and 34 female, adult, healthy dogs of different breeds were studied for erythrocytic G‐6‐PD activity. The hemolysates were also studied electrophoretically for G‐6‐PD, 6‐PGD, and hemoglobin variants. Most of the plasma samples revealed a human Hp 1–1 type of band while three samples had an additional fast‐moving band that disappeared on addition of an excess of hemoglobin and two samples were ahaptoglobinemic. G‐6‐PD deficiency was detected in eight samples, and it was more frequent in males than in females. The implications of G‐6‐PD deficiency with no difference in the electrophoretic pattern and of ahaptoglobinemia are discussed with respect to different genetic and clinical possibilities.