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Genetic control of liver esterase forms in chickens
Author(s) -
Okada Ikuo,
Sasaki Shigeru
Publication year - 1970
Publication title -
animal blood groups and biochemical genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0003-3480
DOI - 10.1111/j.1365-2052.1970.tb01160.x
Subject(s) - esterase , biology , locus (genetics) , allele , phenotype , acid phosphatase , isozyme , alkaline phosphatase , genetics , microbiology and biotechnology , enzyme , biochemistry , gene
Summary Six regions of esterase activity designated I to VI were resolved from liver extracts of chickens by horizontal starch gel electrophoresis. These esterases were further characterized on the basis of their substrate affinities and differential responses to various inhibitors. Genetic variation was found in esterases of region VI which appeared to be ali‐esterase. Four phenotypes, A, B, AB and O, were observed. These phenotypes were shown to be controlled by one autosomal locus, designated Es‐3 , with alleles Es‐3 A , Es‐3 B and Es‐3 O . This locus is not closely linked to the blood group loci A and B , serum alkaline phosphatase ( Ap ), liver acid phosphatase ( Acp‐2 ) and serum esterase ( Es‐1 ) loci.