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Validation of cardiac output measurement with the LiDCO TM pulse contour system in patients with impaired left ventricular function after cardiac surgery *
Author(s) -
Mora B.,
Ince I.,
Birkenberg B.,
Skhirtladze K.,
Pernicka E.,
Ankersmit H. J.,
Dworschak M.
Publication year - 2011
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2011.06754.x
Subject(s) - medicine , cardiac output , ejection fraction , bolus (digestion) , cardiac function curve , correlation coefficient , cardiology , cardiac surgery , anesthesia , hemodynamics , heart failure , mathematics , statistics
Summary After cardiac surgery, patients with low left ventricular ejection fraction probably benefit the most from accurate monitoring of continuous cardiac output. Thirty patients with impaired ventricular function were studied, and intermittent bolus thermodilution and continuous pulse contour (LiDCO plus TM ) cardiac output compared. Following lithium dilution calibration, a total of 220 paired results were recorded. Thermodilution and LiDCO measurements ranged from 2.3 to 11.0 and 2.6 to 10.8 l.min −1 , respectively. Corresponding means (SD) were 6.1 (1.6) and 6.2 (1.9) l.min −1 , with coefficients of variance of 26 and 31%, respectively. The correlation coefficient was 0.82, bias 0.28 l.min −1 with upper and lower limits of agreement 1.96 and −1.41 l.min −1 ; the percentage error was 27%. LiDCO showed good correlation, marginal bias and acceptable limits of agreement and percentage error. It could therefore potentially replace thermodilution as a means of measuring cardiac output in the ICU, particularly when determination of pulmonary artery pressure is not required.