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Successful resuscitation following ropivacaine‐induced systemic toxicity in a neonate
Author(s) -
Hübler M.,
Gäbler R.,
Ehm B.,
Oertel R.,
Gama de Abreu M.,
Koch T.
Publication year - 2010
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2010.06449.x
Subject(s) - medicine , ropivacaine , bradycardia , anesthesia , resuscitation , heart rate , qrs complex , cardiology , blood pressure
Summary A 5‐week‐old preterm infant was scheduled for inguinal hernia repair. Following induction of general anaesthesia, 10 mg.kg −1 ropivacaine was injected, accidently, into the caudal space. The infant developed cardiac depression with bradycardia (minimum heart rate 50 beats.min −1 ), elevated T waves and widening of QRS complexes. Resuscitation by means of external chest compression, intravenous adrenaline and fluid administration was successful. Ropivacaine serum concentrations were obtained at three time points yielding a peak level of 6 μg.ml −1 20 min after caudal injection.