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Early treatment of a quetiapine and sertraline overdose with Intralipid ® *
Author(s) -
Finn S. D. H.,
Uncles D. R.,
Willers J.,
Sable N.
Publication year - 2009
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2008.05744.x
Subject(s) - medicine , quetiapine , coma (optics) , sertraline , drug overdose , ingestion , anesthesia , resuscitation , toxicity , poison control , psychiatry , schizophrenia (object oriented programming) , emergency medicine , anxiety , physics , optics , antidepressant
Summary We describe the initial management and subsequent recovery of a 61 year‐old male patient following attempted suicide by oral ingestion of a potentially fatal overdose of quetiapine and sertraline. Intravenous Intralipid ® was given soon after initiation of basic resuscitation. There was a rapid improvement in the patient’s level of consciousness. No other clinical signs of drug toxicity were observed. Intralipid may have reversed the deep coma associated with ingestion and prevented other manifestations of drug toxicity occurring, thus expediting this patient's recovery.