Premium
Can state or response entropy be used as a measure of sleep depth?
Author(s) -
Mahon P.,
Greene B. R.,
Lynch E. M.,
McNamara B.,
Shorten G. D.
Publication year - 2008
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2008.05675.x
Subject(s) - medicine , entropy (arrow of time) , statistics , mathematics , thermodynamics , physics
Summary In this prospective observational study we examined the potential of the spectral entropy measures ‘state’ and ‘response’ entropy (Entropy™ monitor), as measures of sleep depth in 12 healthy adult subjects. Both median state and response entropy values varied significantly with sleep stage (p = 0.017 and p = 0.014 respectively; ANOVA). Median state or response entropy did not decrease significantly during the transition from awake to stage I sleep (p > 0.017). State entropy values decreased significantly between sleep stages I and II (p < 0.001). Both state and response entropy values were significantly less (40 and 45 arbitrary units respectively) in stage III (slow wave sleep) vs stage II sleep (p = 0.008). We conclude that state and response entropy values, when expressed as a function of time, may be a useful means of quantifying aspects of sleep.