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Responsiveness to stimuli of bispectral index, middle latency auditory evoked potentials and clinical scales in critically ill children
Author(s) -
Lamas A.,
LópezHerce J.,
Sancho L.,
Mencía S.,
Carrillo Á.,
José Santiago M.,
Martínez V.
Publication year - 2008
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2008.05654.x
Subject(s) - stimulus (psychology) , medicine , audiology , heart rate , auditory stimuli , bispectral index , anesthesia , blood pressure , neuroscience , psychology , perception , cognitive psychology , sedation
Summary We performed simultaneous recordings of Bispectral Index (BIS) and middle latency auditory evoked potentials. We also recorded two clinical scales, the Modified Ramsay scale and the COMFORT scale. Heart rate and blood pressure were measured once a day, for a maximum of 5 days, in 81 critically ill children. Changes with tactile, auditory, and painful stimuli were analysed. All the stimuli significantly increased the BIS value, the painful stimulus having the greatest effect. The painful stimulus was the only one that altered the middle latency auditory evoked potentials. Although the responses of the clinical scales to stimuli were statistically significant, they were of little clinical relevance. None of the stimuli used significantly altered the heart rate or blood pressure. We conclude that tactile, auditory and painful stimuli produced changes of little relevance in the clinical scales, BIS or middle latency auditory evoked potentials. We found the BIS was the most sensitive method and the painful stimulus had the greatest effect.