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Effects of normobaric hyperoxia on haemodynamic parameters of healthy full‐term parturients
Author(s) -
Litchfield K. N.,
Harten J. M.,
Anderson K. J.,
Kinsella J.,
McGrady E. M.
Publication year - 2007
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2007.05150.x
Subject(s) - medicine , cardiac index , hemodynamics , vascular resistance , cardiac output , heart rate , hyperoxia , mean arterial pressure , anesthesia , blood pressure , cardiology , stroke volume , impedance cardiography , lung
Summary Fifteen healthy, full‐term women with singleton pregnancies were exposed to an increased F I o 2 of 0.4 and their haemodynamic responses measured with a non‐invasive transthoracic bio‐impedance monitor. There was a mean reduction in cardiac index from 3.18 to 3.03 l.min −1 .m −2 (4.7%, p = 0.004). The mean indexed systemic vascular resistance increased from 2049 to 2178 dynes.cm −5 .m −2 (5.7%, p = 0.005). There were no significant changes in stroke index, heart rate or mean arterial pressure. This study demonstrates that even a moderate increase in inspired oxygen fraction has significant effects on the cardiovascular system of the term parturient.