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Remifentanil for tracheal tube tolerance: a case control study *
Author(s) -
Machata A. M.,
Illievich U. M.,
Gustorff B.,
Gonano C.,
Fäßler K.,
Spiss C. K.
Publication year - 2007
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2007.05100.x
Subject(s) - remifentanil , medicine , anesthesia , visual analogue scale , sedation , ventilation (architecture) , abdominal surgery , tracheal tube , surgery , intubation , propofol , mechanical engineering , engineering
Summary We assessed the minimal remifentanil dosage required for tracheal tube tolerance in awake and spontaneously breathing patients after major abdominal surgery. Forty postoperative patients received remifentanil 0.1 μg.kg −1 .min −1 , which was reduced in steps of 0.025 μg.kg −1 .min −1 every 30 min. Respiratory response subscore of comfort scale (CSRR), Ramsay sedation scale (RSS), visual analogue scale (VAS), respiratory rate, and minute ventilation were recorded. Spontaneous respiration with no or little response to ventilation (CSRR 2) in co‐operative, oriented and tranquil patients (RSS 2) was defined as the main outcome and study endpoint. Thirty‐one patients (77.5%) reached a CSRR 2 and RSS 2 with remifentanil 0.025 μg.kg −1 .min −1 and nine patients (22.5%) required remifentanil 0.05 μg.kg −1 .min −1 . Analgesia was sufficient in all patients (VAS = 30). Remifentanil 0.025−0.05 μg.kg −1 .min −1 achieves satisfactory tracheal tube tolerance in awake and spontaneously breathing patients.