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A comparison of intubating conditions in children following induction of anaesthesia with propofol and suxamethonium or propofol and remifentanil
Author(s) -
Morgan J. M.,
Barker I.,
Peacock J. E.,
Eissa A.
Publication year - 2007
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2006.04903.x
Subject(s) - medicine , remifentanil , propofol , anesthesia , intubation , laryngoscopy , tracheal intubation , heart rate , hemodynamics , blood pressure , general anaesthesia , elective surgery , muscle relaxation , surgery
Summary Sixty ASA 1 and 2 children aged between 2 and 16 years who required tracheal intubation as part of anaesthesia for elective surgery were studied. We evaluated intubating conditions, haemodynamic responses and duration of apnoea following propofol 4 mg.kg −1 combined with either remifentanil 1.25 μg.kg −1 (group R), or suxamethonium 1 mg.kg −1 (group S). Tracheal intubation was graded as excellent, good or poor according to ease of laryngoscopy, vocal cord position, coughing, and jaw relaxation and limb movement. Thirty of group S and 28 of group R children were successfully intubated on the first attempt. Overall, intubation conditions were excellent or good in 26/30 (87%) patients in group S and 20/30 (67%) in group R (p < 0.05). Mean apnoea time was 190 s in group S, and 362 s in group R (p < 0.001). Heart rate increased in response to suxamethonium (p < 0.01) and both systolic and diastolic blood pressure decreased in the remifentanil group (p < 0.01).