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The effect of positive end expiratory pressure on the respiratory profile during one‐lung ventilation for thoracotomy *
Author(s) -
Leong L. M. C.,
Chatterjee S.,
Gao F.
Publication year - 2007
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2006.04893.x
Subject(s) - medicine , positive end expiratory pressure , oxygenation , anesthesia , ventilation (architecture) , tidal volume , thoracotomy , pulmonary compliance , lung , lung volumes , respiratory system , mechanical ventilation , cardiology , mechanical engineering , engineering
Summary In this randomised controlled trial we examined the effects of four different levels of positive end expiratory pressure (PEEP at 0, 5, 8 or 10 cmH 2 O), added to the dependent lung, on respiratory profile and oxygenation during one lung ventilation. Forty‐six patients were recruited to receive one of the randomised PEEP levels during one lung ventilation. We did not find significant differences in lung compliance, intra‐operative or postoperative oxygenation amongst the four different groups. However, the physiological deadspace to tidal volume ventilation ratio was significantly lower in the 8 cmH 2 O PEEP group compared with the other levels of PEEP (p < 0.0001). We concluded that the use of PEEP (≤10 cmH 2 O) during one lung ventilation does not clinically improve lung compliance, intra‐operative or postoperative oxygenation despite a statistically significant reduction in the physiological deadspace to tidal volume ratio.