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A randomised double‐blind controlled study evaluating the hypothermic effect of 150 μg morphine during spinal anaesthesia for Caesarean section
Author(s) -
Hui C.K.,
Huang C.H.,
Lin C.J.,
Lau H.P.,
Chan W.H.,
Yeh H.M.
Publication year - 2006
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2005.04466.x
Subject(s) - medicine , caesarean section , anesthesia , spinal anesthesia , morphine , pregnancy , genetics , biology
Summary We studied the hypothermic effect of adding 150 μg morphine during spinal anaesthesia in 60 parturients scheduled for elective caesarean section. All the parturients received intrathecal injection of a solution containing 150 μg morphine or normal saline in addition to 10–12 mg hyperbaric bupivacaine 0.5%. In both groups, a significant decrease in body temperature was noted. There was no difference in the area under the curve for temperature against time for the two groups; however, the maximum decrease in temperature from baseline was significantly larger after morphine than after saline injection (mean (SD) 1.11 (0.61) °C vs 0.76 (0.39) °C, respectively; p = 0.01) and the time to nadir temperature was significantly longer (59.5 (17.6) min vs 50.4 (15.9) min, respectively; p = 0.047). The lowest temperature observed in the morphine group was 34.3 °C. We conclude that intrathecal injection of 150 μg morphine intensified the intra‐operative hypothermic effect of bupivacaine spinal anaesthesia for caesarean section.