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A comparison of the insertion characteristics of the laryngeal tube and the laryngeal mask airway: a study of the ED50 propofol requirements
Author(s) -
Burlacu C. L.,
Gaskin P.,
Fernandes A.,
Carey M.,
Briggs L.
Publication year - 2006
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2005.04442.x
Subject(s) - propofol , medicine , alfentanil , anesthesia , laryngeal mask airway , mascara , ed50 , airway , bolus (digestion) , larynx , laryngeal masks , surgery , tracheal tube , receptor
Summary The purpose of this prospective randomised double‐blind study was to determine the effective dose of propofol required for the successful first attempt insertion of the laryngeal tube compared with the laryngeal mask airway in patients co‐induced using alfentanil 5 μg.kg –1 , undergoing short elective gynaecological procedures. The first patient in each group received propofol 2.5 mg.kg −1 for induction. In accordance with Dixon's up‐and‐down method, the dose of propofol for consecutive patients in each group was varied with increments or decrements of 0.5 mg.kg −1 based on the previous patient ‘all‐or‐none’ purposeful movement response to first attempt of insertion of the randomised device. The ED50 (SD) of propofol was 2.66 (0.86) mg.kg −1 and 2.33 (0.37) mg.kg −1 for the laryngeal tube and laryngeal mask patients, respectively, which did not reach statistical significance (p = 0.40). We conclude therefore that the insertion of the two airway devices requires similar bolus doses of propofol when alfentanil is used as the co‐induction drug.