Premium
Predictors of long‐term mortality and cardiac events in patients with known or suspected coronary artery disease who survive major non‐cardiac surgery
Author(s) -
Filipovic M.,
Jeger R. V.,
Girard T.,
Probst C.,
Pfisterer M.,
Gürke L.,
Studer W.,
Seeberger M. D.
Publication year - 2005
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.2004.03996.x
Subject(s) - medicine , odds ratio , confidence interval , cardiology , cardiac surgery , coronary artery disease , heart failure , logistic regression , troponin , mortality rate , prospective cohort study , surgery , myocardial infarction
Summary The aim of this prospective study was to assess predictors of long‐term outcome in patients with documented or suspected coronary artery disease who survive major non‐cardiac surgery. The impact of patients' comorbidities, pre‐operative heart rate variability and postoperative increase in cardiac troponin I on all‐cause mortality and major cardiac events within 2 years was explored using multivariable logistic regression. Six of 173 patients died within the first month after surgery and were excluded from the study. Thirty‐four of 167 patients (20%) died 1–24 months after surgery. Independent predictors of all‐cause mortality were history of congestive heart failure (odds ratio 6.4 [95%, confidence interval 1.7–24]), pre‐operatively depressed heart rate variability (odds ratio 6.4 [95%, confidence interval 1.9–21]), and age > 70 years (odds ratio 4.5 [95%, confidence interval 1.2–16]). In contrast, postoperative elevation of cardiac troponin I did not independently predict all‐cause mortality or major cardiac events.