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New agents, the circle system and short procedures
Author(s) -
Nel M. R.,
Ooi R.,
Lee D. J. H.,
Soni N.
Publication year - 1997
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1997.az0083a.x
Subject(s) - desflurane , isoflurane , sevoflurane , medicine , anesthesia , fresh gas flow , volatile anesthetic
Sevoflurane, desflurane and isoflurane were compared using a circle system in 97 patients undergoing short surgical procedures. Using initial high flows, the time intervals to equilibration between inspired and end‐expired agent concentrations were measured; equilibration was defined as F E / F 1 =0.8. The mean (SD) times obtained for sevoflurane, desflurane and isoflurane were 8.2 (2.1) min, 3.8 (0.7) min and 19.7 (6.5) min, respectively. These times were significantly different from each other (p <0.0001). After equilibration total flows were reduced to 500 ml.min −1 ; at these flows the initial decline in end‐expired agent concentration was minimal with desflurane, intermediate with sevoflurane and greatest with isoflurane. Both desflurane and sevoflurane are appropriate for efficient use of the circle system during short anaesthetics.