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Predictors of postoperative myocardial ischaemia The role of intercurrent arterial hypertension and other cardiovascular risk factors
Author(s) -
Howell S. J.,
Hemming A. E.,
Allman K. G.,
Glover L.,
Sear J. W.,
Foe¨x P.
Publication year - 1997
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1997.29-az029.x
Subject(s) - medicine , odds ratio , confidence interval , blood pressure , cardiology , risk factor , ischemia , anesthesia
One hundred and eighty‐three patients were studied to examine the role of a number of risk factors in the development of silent ischaemia after general anaesthesia for general and vascular surgery. We collected evidence of cardiovascular risk factors using a binary questionnaire. The patients were monitored pre‐ and postoperatively using a Holter ECG monitor. Usable data were collected on 140 patients. Pre‐operative silent myocardial ischaemia was found to be strongly associated with postoperative silent myocardial ischaemia (odds ratio: 10.8, 95% confidence intervals: 3.8–30.7). A history of hypertension, indicated by treatment with antihypertensive drugs, was associated with increased risk (odds ratio: 2.58, 95% confidence intervals: 1.12–5.96). A linear trend was found for risk associated with increasing admission systolic blood pressure (odds ratio: 1.20 for each 10‐mmHg increase in systolic pressure, 95% confidence intervals: 1.01–1.42). An association between vascular surgery and postoperative silent myocardial ischaemia was also confirmed (odds ratio: 2.36, 95% confidence intervals: 1.1–5.1).