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Event‐related evoked potential responses (P 300 ) following epidural methylprednisolone therapy in chronic low back pain patients
Author(s) -
Tandon O. P.,
Kumar A.,
Dhar D.,
Battacharya A.
Publication year - 1997
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1997.228-az0363.x
Subject(s) - medicine , methylprednisolone , anesthesia , visual analogue scale , epidural administration , chronic pain , physical therapy , bupivacaine
P 300 event‐related potentials were recorded in 12 patients with chronic low back pain following epidural methylprednisolone administration. The values of absolute peak latencies and amplitudes of P 300 were recorded before (baseline) and on the 5th and 10th days following epidural injection. Intensity of pain was also recorded using a 10‐cm visual analogue scale score. The absolute peak latency of P 300 significantly decreased on the 5th and 10th days following epidural methylprednisolone (p < 0.001) when compared with baseline value. Visual analogue scores also decreased significantly (p < 0.001) after the 5th and 10th days of epidural methylprednisolone. These observations suggest that following epidural methylprednisolone administration in chronic low back pain patients, significant improvement in cognitive functions and pain relief go hand in hand.