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Lack of efficacy of intra‐articular opioids for analgesia after day‐case arthroscopy
Author(s) -
WRENCH I. J.,
TAYLOR P.,
HOBBS G. J.
Publication year - 1996
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1996.tb14957.x
Subject(s) - medicine , analgesic , buprenorphine , morphine , anesthesia , placebo , knee arthroscopy , saline , intra articular , opioid , arthroscopy , clinical trial , surgery , osteoarthritis , receptor , alternative medicine , pathology
Summary A randomised double‐blind placebo‐controlled trial was undertaken to assess the analgesic efficacy of intra‐articular opioids following arthroscopy of the knee. At the completion of surgery, patients received an intra‐articular injection of: morphine 1 mg, buprenorphine 30 μg or 0.9% saline. There were no differences in pain scores among groups for the first 24 h postoperatively. We have found no clinical evidence for a peripherally‐mediated opioid analgesic effect.