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Control of end‐tidal carbon dioxide during IPPV
Author(s) -
SCOTT P. V.,
HADEN R. M.,
JONES R. P.
Publication year - 1996
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1996.tb07890.x
Subject(s) - tidal volume , medicine , carbon dioxide , anesthesia , ventilation (architecture) , respiratory minute volume , general anaesthesia , mechanical ventilation , respiratory system , meteorology , ecology , physics , biology
Summary We have described a method for control of end‐tidal carbon dioxide tension during intermittent positive pressure ventilation in a model lung and in 19 adults during general anaesthesia supplemented by central or peripheral neural blockade. The inspiratory and expiratory limbs of an open or a circle anaesthesia system were interconnected and ventilated simultaneously in a variable manner during inspiration. The flow of mixed‐expired gas, normally one‐way, became to‐and‐fro (variable functional apparatus deadspace, or‘virtual’deadspace). At minute volume ventilation > = 100 ml.kg ‐1 .min ‐1 (patients), the value of end‐tidal carbon dioxide tension was varied reproducibly within the range 4.1–6.5 (SD 0.1) kPa independently of fresh gas flow or other prescribed patterns of ventilation. At a steady state, stable nominated values of end‐tidal carbon dioxide tension within the range were attained. By how much any given intra‐operative value of end‐tidal carbon dioxide tension may be said to affect peri‐operative outcome is debatable, but during surgery any change in a nominated value may usefully indicate a change in the steady state.