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The effect of temperature upon pain during injection of propofol
Author(s) -
Fletcher G. C.,
Gillespie J. A.,
Davidson J. A. H.
Publication year - 1996
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1996.tb07802.x
Subject(s) - propofol , medicine , anesthesia , incidence (geometry) , injection site , postoperative pain , surgery , physics , optics
Summary Propofol has been shown to cause pain on injection. This study investigated the effect of warming propofol to 37°C on the pain of intravenous injection. One hundred and one women on outpatient gynaecology lists were allocated to receive propofol either at room temperature or at 37°C. Warming propofol decreased the incidence of pain on injection by 37% (p < 0.001), and also decreased the severity of pain reported by patients (p < 0.001). We conclude that warming propofol to 37°C provides a simple and safe method of reducing the incidence of pain on injection without the addition of other agents.