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Modification of pain on injection of propofol
Author(s) -
Lyons B.,
Lohan D.,
Flynn C.,
McCarroll M.
Publication year - 1996
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1996.tb07756.x
Subject(s) - medicine , pethidine , propofol , anesthesia , placebo , lidocaine , saline , surgery , analgesic , alternative medicine , pathology
Summary One hundred and fifty ASA 1 and 2 patients were randomly allocated to receive pethidine 25 mg (1 ml), lignocaine Wing (1 ml) or 0.9% saline (1 ml) on a double‐blind basis, as pretreatment to reduce pain on injection of propofol. Both active treatments were significantly better than placebo at preventing pain (p<0.01). Lignocaine was most effective in preventing pain in men (p<0.05) whilst pethidine was more effective in women (p<0.05).