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The effect of prophylactic clonidine on postoperative shivering
Author(s) -
VANDERSTAPPEN I.,
VANDERMEERSCH E.,
VANACKER B.,
MATTHEUSSEN M.,
HERIJGERS P.,
AKEN H.
Publication year - 1996
Publication title -
anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.839
H-Index - 117
eISSN - 1365-2044
pISSN - 0003-2409
DOI - 10.1111/j.1365-2044.1996.tb07747.x
Subject(s) - shivering , clonidine , medicine , anesthesia , sedation , blood pressure , placebo , heart rate , hemodynamics , surgery , alternative medicine , pathology
Summay The primary goal of this study was to assess the influence of clonidine administered after induction on postoperative shivering after elective peripheral surgery. The effect of clonidine on intra‐operative haemodynamics (blood pressure and heart rate) during the first 30 min after induction and on the postoperative sedation of the patient was also investigated. Two hundred and eighty male ASA 1 and 2 patients, undergoing elective peripheral surgery were randomly administered either placebo or clonidine 2 μg.kg ‐1 intravenously over 10 min after induction of anaesthesia. Clonidine was found to reduce the total incidence (p = 0.024), the severity (p = 0.005) and the duration (p= 0.01) of postoperative shivering. Clonidine did not increase postoperative sedation or diminish overall consciousness. We conclude that administration of clonidine 2 μg.kg ‐1 intravenously after induction of anaesthesia is safe and reduces postoperative shivering in this group of patients.